LYODIS – ORAL LYOPHILIZATES

LyoDis®

Produced on the Galien LPS Nevers site, the orodispersible lyophilisate is a porous solution containing an active ingredient dispersed on an alveolar structure.

Very hydrophilic, it dissolves and disperses instantly in the mouth on contact with saliva.
It can therefore be taken directly without adding additional water. The oral lyophilisate retains all the specificities of the starting liquid preparation.

This technology can relate to all active principles and all drugs prescribed or dispensable without prescription, or even veterinary products.

It gives you a commercial and competitive advantage.
With this technology, we can offer you the exclusivity of your molecule.


Instant disintegration


Administration without water


Wide range of active substance load


Enhanced stability (3/5 years)


Suitable for most patients


Instant disintegration


Administration without water


Enhanced stability (3/5 years)


Suitable for most patients


Wide range of active substance load

Practical and therapeutic benefits

  • Speed of action: the almost instant dissolution of LyoDis® in the mouth and the very fast availability of the active ingredient can allow oral absorption of the active ingredient and therefore earlier therapeutic action.
  • Administration without water: avoids the exacerbations of the gag reflex encountered in many pathologies.
  • Convenience of use: LyoDis® can be taken as soon as symptoms appear, at any time and in any circumstances. The LyoDis® is particularly suitable for outpatient treatment, children, the elderly and in patients with swallowing problems.
  • Absorption by mouth is also an advantage for drugs metabolized by the liver by avoiding the first pass liver effect.
  • The absence of sucrose and sodium makes LyoDis® very easy to handle in patients with diabetes, hypertension, or heart failure.

Pharmaceutical benefits

  • Increased stability: LyoDis® improves stability, both chemical and physical. It allows both to keep the qualities of the active ingredients and to keep them in their optimum state of activity.
  • Instant solubility: the high porosity of LyoDis® and its hydrophilicity allow disintegration and accelerated dissolution. The active ingredient disperses in a fine and homogeneous way.
  • Fewer adjuvants: lyophilization decreases the amount of functional adjuvants such as preservatives, carbohydrate excipients or sodium-based compounds. It consists almost exclusively of the active ingredient.
  • Thanks to associated technologies, LyoDis® can make it possible to combine active ingredients that had previously been chemically or physically incompatible, to develop micronized or coated products and to mask their taste.